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Monday, December 15, 2008

How to Pick Athletic Superstars at Age 1


Of all of the decisions parents face regarding their children's future, choosing between shoulder pads or running shoes for their Christmas present seems trivial. Well, according to Kevin Reilly, president of Atlas Sports Genetics, this is a decision you should not take lightly.
"If you wait until high school or college to find out if you have a good athlete on your hands, by then it will be too late," he said in a recent New York Times interview. "We need to identify these kids from 1 and up, so we can give the parents some guidelines on where to go from there."
Two weeks ago, Reilly's company began marketing a $149 saliva swap test for kids, aged 1 to 8, to determine which variant of the gene ACTN3 is in their DNA. According to a 2003 Australian study, ACTN3 was shown to be a marker for two different types of athletic prowess, explosive power or long endurance. While everyone carries the gene, the combination of variants inherited, one from each parent, differs.
The R variant of ACTN3 signals the body to produce a protein, alpha-actinin-3, which is found exclusively in fast-twitch muscles. The X variant prohibits this production. So, athletes inheriting two R variants may have a genetic advantage in sports requiring quick, powerful muscle contractions from their fast-twitch muscle fibers.
In the ACTN3 study, Dr. Kathryn North and her lab at the Institute for Neuromuscular Research of the University of Sydney looked at 429 internationally ranked Australian athletes and found significant correlation between power sport athletes and the presence of the R variant. All of the female sprint athletes had at least one R variant, as did the male power-sport athletes. In fact, 50 percent of the 107 sprinters had two copies of the R variant.
What about those aspiring athletes that were not fortunate enough to inherit the R variant and its protein producing qualities?
North's team also noted that the elite endurance athletes seemed to be linked to the XX variation, although only significantly in the female sample. In 2007, her team pursued this link by developing a strain of mice that was completely deficient in the alpha-actinin-3 protein similar to an athlete with an XX allele. They found the muscle metabolism of the mice without the protein was more efficient. Amazingly, the mice were able to run 33 percent farther than mice with the normal ACTN3 gene.

Additional research is showing mixed results, however. Read the rest of the article here...

http://www.livescience.com/culture/081215-sports-genetic-testing.html

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