Creating a living, breathing creature from a genome sequence that exists only in a computer's memory is not possible right now. But someone someday is sure to try it, predicts Stephan Schuster, a molecular biologist at Pennsylvania State University, University Park, and a driving force behind the mammoth genome project.
So besides the mammoth, what other extinct beasts might we coax back to life? Well, it is only going to be possible with creatures for which we can retrieve a complete genome sequence. Without one, there is no chance. And usually when a creature dies, the DNA in any flesh left untouched is soon destroyed as it is attacked by sunshine and bacteria.
There are, however, some circumstances in which DNA can be preserved. If your specimen froze to death in an icy wasteland such as Siberia, or snuffed it in a dark cave or a really dry region, for instance, then the probability of finding some intact stretches of DNA is much higher.
Even in ideal conditions, though, no genetic information is likely to survive more than a million years - so dinosaurs are out - and only much younger remains are likely to yield good-quality DNA. "It's really only worth studying specimens that are less than 100,000 years old," says Schuster.
The genomes of several extinct species besides the mammoth are already being sequenced, but turning these into living creatures will not be easy (see "Revival recipe"). "It's hard to say that something will never ever be possible," says Svante Pääbo of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, "but it would require technologies so far removed from what we currently have that I cannot imagine how it would be done."
But then 50 years ago, who would have believed we would now be able to read the instructions for making humans, fix inherited diseases, clone mammals and be close to creating artificial life? Assuming that we will develop the necessary technology, we have selected 10 extinct creatures that might one day be resurrected. Our choice is based not just on feasibility, but also on each animal's "megafaunal charisma" - just how exciting the prospect of resurrecting these animals is.
Of course, bringing extinct creatures back to life raises a whole host of practical problems, such as where they will live, but let's not spoil the fun...
http://www.newscientist.com/article/mg20126905.000-ten-extinct-beasts-that-could-walk-the-earth-again.html?DCMP=OTC-rss&nsref=life
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